5 Best Depression and Fatigue Relief Supplements for Women With PMS

PMS (premenstrual syndrome) refers to a group of symptoms that occur a week or two before a woman gets her period. While the exact cause of these symptoms isn't known, they seem to be triggered by fluctuating hormone levels, especially after ovulation.

PMS symptoms include mood swings, irritability, depression, anxiety, fatigue, headache, low libido, breast pain, etc.

Although these symptoms can be difficult to deal with, the right supplements with active ingredients that work on these hormones may provide relief from PMS symptoms.

Here are the 5 best depression and fatigue relief supplements from Approved Science.

5 Best PMS Depression and Fatigue Relief Supplements

• Best for Mood: Adrenasyl™
• Best for Fatigue: Energysyl™
• Best for Depression Management: Testosterone Booster
• Best for Stress Management: Ashwagandha™
• Best for Cognitive Support: Mushroom Complex

1. Best for Mood



Adrenal glands play a very important part in managing your mood, as they secrete stress hormones and are involved in the fight-or-flight response.

Targeting adrenal glands, Approved Science’s Adrenasyl™ contains a blend of 5 adaptogenic mushrooms, B-complex vitamins, vitamin C, selenium, and adrenal-supportive herbs to improve your mood.

The supplement also contains Bioperine, which is a unique compound hardly found in any other supplement that increases the absorption by 1.5 times. This is Approved Science's patented form of piperine, the active compound found in black pepper.

By providing the right nutrients, Adrenasyl™ promotes better response to daily stressors, combats adrenal fatigue, and boosts energy levels. The powerful adaptogenic herbs balance the fluctuating hormonal levels during PMS.

» Improve your mood with Adrenasyl™

2. Best for Fatigue



Fatigue is one of the most common PMS symptoms experienced by most women.

Your body tends to tire out after encountering continuous physical and psychological stressors, and the fatigue sets in, as your body is left with a lack of cortisol and serotonin after combating stress.

Designed to address this issue, Approved Science's Energysyl™ contains adaptogenic herbs and medicinal mushrooms that fight fatigue, boost metabolism, and increase energy. These are Siberian Ginseng, Ashwagandha, Reishi, and Cordyceps mushrooms.

The eight B vitamins in Energysyl™ increase energy production and its utilization. Its Bioperine content increases nutrient bioavailability and absorption.

The bioavailable form of vitamins B6 and B9 help increase serotonin production improving mood. The medicinal properties of the herbs and mushrooms in this supplement also reduce the amount of time needed to recover from physical and mental strain.

» Fight fatigue symptoms with Energysyl™

3. Best for Depression Management



Women who don't experience the normal spike in their testosterone levels during their menstrual cycle can face premenstrual testosterone deficiency symptoms.

As testosterone has both antidepressant and anxiolytic properties, a supplement that naturally boosts testosterone production can be the right solution to improve mood and help manage depression. One such supplement is Approved Science's Testosterone Booster, which has 1500 mg of clinically proven ingredients that boost testosterone levels, such as Tribulus Terrestris, Tongkat Ali, zinc, magnesium, and vitamin B6 blend (ZMA).

Apart from offering some relief for PMS symptoms, testosterone boosters can also promote lean muscle mass, help in weight management, improve mood and cognitive function, reduce inflammation, and lower gastrointestinal problems.

» Manage depression with Testosterone Booster

4. Best for Stress Management



Ashwagandha has long been used as an adaptogen that helps manage and counter stress, as it contains a phytochemical that helps lower cortisol, reduce stress and depression, improve sleep, soothe inflammation, and enhance your overall health.

Approved Science's Ashwagandha helps combat stress by simultaneously calming the mind and energizing the body. It also helps alleviate insomnia symptoms and improve mood and cognitive functions such as concentration and focus.

In addition to that, the active ingredients in Ashwagandha™ protect against cognitive decline and memory loss, while its strong anti-inflammatory properties can reduce pain resulting from inflammation.

» Reduce stress levels with Ashwagandha

5. Best for Cognitive Support



Medicinal mushrooms provide a range of health benefits, including boosting antioxidants, increasing energy, strengthening immunity, and enhancing cognitive energy. They improve memory, promote concentration, and slow down brain aging.

Making use of these benefits, Advanced Science's Mushroom Complex has 10 varieties of powerful medicinal mushrooms that reduce inflammation and provide maximum cognitive support by stimulating nerve cell growth and improving memory and focus.

Among their other benefits, medicinal mushrooms can also support healthy blood sugar levels, reduce the risk of heart disease, and help relieve pain associated with inflammation, such as joint pain.

» Improve your memory and focus with Mushroom Complex

Fight PMS Depression and Fatigue With the Right Supplements

PMS affects women in different ways—while some experience headaches and breast tenderness, others may be suffering from fatigue, depression, and irritability.

Supplements with medicinal mushrooms, ashwagandha, omega-3, B vitamins, etc. can help balance hormones, reduce stress, and offer relief from the depression and fatigue associated with PMS. If you're experiencing these issues, make sure to make a pick from our list based on your particular needs.