5 Energy-Boosting and Anti-aging Supplements to Improve Mitochondrial Health

Anju Mobin
By Anju Mobin
Joel Taylor
Edited by Joel Taylor

Published August 31, 2022.

A bunch of white-and-blue capsules falling onto a reflect surface, in front of a grey background.

The mitochondria are responsible for cellular energy production that fuels all our bodily functions. Mitochondrial dysfunction occurs when the mitochondria are not able to work the way they should and can be due to underlying medical conditions or diseases. When energy production gets hampered, it causes a host of undesirable symptoms affecting any and all organs.

Clinical trials have shown that supplements such as L-carnitine, alpha-lipoic acid, coenzymeQ10, and magnesium malate can improve mitochondrial health and restore its functions.

This article looks at 5 particular supplements and their efficiency in improving mitochondrial health.

5 Supplements That Support Mitochondria

1. α-Lipoic Acid (1,2-dithiolane-3-pentanoic acid)

This is a well-known fatty acid and a strong antioxidant that helps regulate metabolism, produce energy, and boost mitochondrial processes. Alpha-lipoic acid is naturally present in mitochondria and serves as a cofactor for enzymes that help produce adenosine triphosphate (ATP), the energy currency.

The antioxidant property of alpha-lipoic acid prevents excess free radical production and helps improve mitochondrial function. Studies have observed that supplements of α-Lipoic acid can renew mitochondrial activity (1).

2. L-Carnitine

L-carnitine helps in the transportation of fatty acids into the mitochondria, where they are oxidized to generate energy. L-carnitine is made from the amino acids lysine and methionine.

Therefore, a deficiency of L-carnitine can lead to reduced mitochondrial function. L-carnitine supplements potentially improve mitochondrial health, increase overall energy production, and reduce exercise-induced fatigue (2).

3. Coenzyme Q10 (Ubiquinone)

Coenzyme Q10 helps stabilize the membranes around the mitochondria and supports the conversion of food into energy.

Supplementing with CoQ10 has been shown to improve mitochondrial activity and also enhance the antioxidant ability of the mitochondria (3). Coenzyme Q10 supplements are also suitable for supporting your aging brain.

For more info about this supplement, take a look at the following posts:

4. Glutathione

Glutathione is a strong antioxidant made naturally by the body and is present in mitochondria (4). It prevents free radicals and other harmful particles from entering, while also helping to repair damage to the mitochondria. Glutathione is made from three amino acids:

  1. Cysteine
  2. Glutamate
  3. Glycine

Where you are deficient in glutathione, food and supplements can help. Consider taking a look at Approved Science Glutathione which helps eliminate unhealthy toxins and free radicals, reducing cell damage.

Glutathione is also one of the best antioxidant supplements.

5. Omega-3 Fatty Acids

The outer layer of the mitochondria is made of fats. Therefore, supplementing with omega-3 fatty acids can help support and strengthen the structure of the membrane and make it stronger. They also support energy production. Approved Science Omega-3 has shown tremendous benefit in this respect.

Other Nutrients That Mitochondria Need to Thrive

Keeping your mitochondria in good health is crucial. Vitamins B1, B2, B6, niacin, biotin, folic acid, and pantothenic acid are essential in the functioning of the mitochondria. Vitamin C, E, niacin, and folic acid help prevent oxidative damage to the mitochondria.

Glutathione, a natural antioxidant produced by the body, also protects the mitochondria. High-protein foods such as meat, fish, eggs, nuts, and seeds help boost glutathione production.

Healthy fats that have omega-3 fatty acids support the health and function of the cells and the mitochondria by increasing the efficiency of energy metabolism. Phytonutrients from plants are potent antioxidants and keep the mitochondria safe from external stimuli.

Conclusion

Mitochondria is a very important organelle of human cells that produces energy to fuel every function in the body. Therefore, keeping your mitochondria healthy is crucial.

Age, infections, and lifestyle changes can destroy these cell organelles and can cause severe problems.

Intervention with the correct supplement, such as L-carnitine, omega-3s, and glutathione, can improve mitochondrial health.